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Urelumab Biosimilar – Research Grade [ICH5015]

Rated 5.00 out of 5 based on 1 customer rating

$718.00 – $4,161.00

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Urelumab Biosimilar – Research Grade [ICH5015]
SKU: ICH5015 Categories: anti-human, Biosimilar Antibodies, Low Endotoxin
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Urelumab Biosimilar – Research Grade

Product Details:

ichorbio’s urelumab biosimilar is for Research Use Only (RUO) and not for therapeutic use.

Size:

ichorbio’s RUO urelumab biosimilar is available in the following sizes:
0.1mg, 5mg, 10mg, 20mg, 50mg
ichorbio regularly manufactures bulk multi-gram amounts of this biosimilar – please contact us for pricing.

Target:

4-1BB

Clone:

n/a

Isotype:

IgG4 (S228P)-kappa

Other Names:

4-1BB ligand receptor, T-cell antigen 4-1BB, Tnfrsf9, Ila, Ly63, CD137

Host:

CHO

Species Reactivity:

Human

Specificity:

Detects human 4-1BB. This non-therapeutic antibody uses the same variable region sequence as the therapeutic antibody urelumab.

Purification Method:

This recombinant protein was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.

Background:

RUO urelumab is a humanized agonistic monoclonal antibody targeting 4-1BB with potential immunostimulatory and antineoplastic activities. Urelumab specifically binds to and activates CD137-expressing immune cells, stimulating an immune response, in particular a cytotoxic T cell response, against tumor cells. .

Concentration:

1.0 – 5.0 mg/ml

Formulation:

Sterile, preservative-free, solution in PBS. BSA and Azide free.

Purity:

>95% by SDS-PAGE and HPLC

Endotoxin:

≤ 1.0 EU/mg as determined by the LAL method

Storage:

Urelumab Biosimilar – Research Grade is stable for at least four (4) weeks when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at –80°C. Avoid Repeated Freeze Thaw Cycles.

Applications:

Functional Assays

Application Notes:

Each investigator should determine their own optimal working dilution for specific applications.

Use:

ichorbio’s urelumab biosimilar is for research use only (RUO): it is not for diagnostic or therapeutic procedures and cannot be purchased by patients.

Isotype Control:

Bulk Human IgG4 Isotype Control S228P (IB4) [ICH2257S228P]

Size:

0.1mg, 5mg, 10mg, 20mg, 50mg

Endotoxin Level:

Low

1 review for Urelumab Biosimilar – Research Grade [ICH5015]

  1. Rated 5 out of 5

    Mickey Pentecost (verified owner) – March 30, 2022

    Worked perfectly in a 4-1BB signaling bioassay.

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