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Rituximab Biosimilar (LALAPG) - Research Grade
$315.00 - $5,200.00
Rituximab Biosimilar (LALAPG) - Research Grade
Endotoxin
≤ 1.0 EU/mg as determined by the LAL method
Purity
>95% by SDS-PAGE and HPLC
Species Reactivity
Human
Target
CD20
Concentration
1.0 - 5.0 mg/ml
Isotype
Human IgG1 (LALAPG)-Kappa
Host
CHO Cells
Use
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
Storage
Stable for at least one week when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at -80°C. Avoid Repeated Freeze Thaw Cycles.
Formulation
Phosphate buffered saline (PBS) pH 7.2,with no carrier protein, potassium or preservatives added. BSA and Azide free.
Purification Method
This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
Specificity
Detects human CD20. This non-therapeutic antibody uses the same sequence as the therapeutic antibody Rituximab.
Shipping Conditions
Blue ice
Background
CD20 is a hallmark B-cell surface marker widely targeted in lymphoma and autoimmunity research. Carrying the LALAPG Fc mutations that abolish effector function, this research-grade anti-human CD20 recombinant monoclonal antibody is an unconjugated, non-therapeutic analog of rituximab built around the CD20 target for research use only. The effector-silenced design makes it valuable for separating binding from Fc-mediated activity, and it is produced to in vivo standards as an ultra-pure, low-endotoxin preparation in scalable milligram to gram quantities for high-throughput and bulk laboratories. It supports preclinical work spanning binding and blocking assays, in vitro screening, and in vivo B-cell models.
Other Names
MS4A1, B1, Bp35, CD20, CVID5, LEU-16, MS4A2, S7, membrane spanning 4-domains A1, FMC7
Uniprot
P11836
Buffer
ICH3001-100ml
ICH3002-100ml
ICH3003-100ml
Sequence
https://www.imgt.org/mAb-DB/
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