Nesvacumab Biosimilar – Research Grade [ICH5010]

ichorbio’s nesvacumab biosimilar is for Research Use Only (RUO) and not for therapeutic use.

ichorbio’s RUO nesvacumab biosimilar is available in the following sizes:
1mg, 5mg, 10mg, 20mg, 50mg, 100mg
ichorbio regularly manufactures bulk multi-gram amounts of this biosimilar – please contact us for pricing.

Angiopoietin 2

IgG1 kappa

ANG2, ANGPT2

CHO cells

Human

Detects human angiopoietin 2. This non-therapeutic antibody uses the same sequence as the therapeutic antibody nesvacumab.

This recombinant protein was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.

RUO nesvacumab  is an experimental monoclonal antibody originally designed for the treatment of cancer. It targets the protein angiopoietin 2. As of May 2017, it is in Phase II clinical trials for the treatment of diabetic macular edema.

1.0 – 5.0 mg/ml

Sterile, preservative-free, solution in PBS. BSA and Azide free.

>95% by SDS-PAGE and HPLC

≤ 1.0 EU/mg as determined by the LAL method

Nesvacumab Biosimilar – Research Grade is stable for at least four (4) weeks when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at –80°C. Avoid Repeated Freeze Thaw Cycles.

Functional Assays

Each investigator should determine their own optimal working dilution for specific applications.