Tilavonemab Biosimilar – Research Grade

-$1.00$5,000.00

Tilavonemab Biosimilar – Research Grade
SKU: ICH5125 Categories: ,

Safety Data Sheet


Version 2.5 SDS Revision Date 8/31/2022
www.ichor.bio


  1. IDENTIFICATION OF THE SUBSTANCE/MIXTURE AND OF THE COMPANY/UNDERTAKING


    1. Product Identifiers


      Product Name: Tilavonemab Biosimilar - Research Grade
      Catalogue Number: ICH5125

    2. Relevant identified uses of the substance or mixture and uses advised against


      Identified Uses:


    3. Details of the supplier of the safety data sheet


      Company: ichorbio Ltd, Boston House, Grove Business Park

      Downsview Road, Wantage, OX12 9FF, UK


      Internet: www.ichor.bio
      Email address: hello@ichor.bio


    4. Emergency Telephone Number


      Emergency Tel: UK: +44 7749 955031


  2. HAZARDS IDENTIFICATION


    1. Classification of the substance or mixture


      This substance does not meet the classification criteria of the EC Directives 67/548/EEC, 1999/45/EC, 1272/2008 [CLP], GHS or 29 CFR 1910.1200 [OSHA].

    2. Label Elements


      The product does not need to be labelled in accordance with EC directives or respective national laws.


    3. Other Hazards


      None


  3. COMPOSITION/INFORMATION ON INGREDIENTS


    1. Substances


      Not applicable

    2. Mixtures


      This product does not contain hazardous chemicals at concentrations of 1% or greater. This product is not known to contain carcinogens at concentrations of 0.1% or greater.


  4. FIRST AID MEASURES


    1. Description of first aid measures General Advice


      Consult a doctor and show this safety data sheet.


      If Inhaled


      Remove to fresh air and monitor breathing. If breathing becomes difficult, give oxygen. If breathing stops, give artificial respiration. Consult a doctor.

      In Case of Skin Contact


      Immediately wash skin with copious amounts of soap and water for at least 15 minutes. Remove contaminated clothing and shoes and wash before reuse. Consult a doctor.

      In Case of Eye Contact


      Flush with copious amounts of water for at least 15 minutes. Consult a doctor.


      If Swallowed


      Rinse mouth with water. Do not induce vomiting unless directed to do so by medical personnel. Never give anything by mouth to an unconscious person. Consult a doctor.

    2. Most important symptoms and effects, both acute and delayed


      To the best of our knowledge, the chemical, physical and toxicological properties have not been thoroughly investigated.


    3. Indication of immediate medical attention and special treatment needed


      Show this safety data sheet to the doctor in attendance. Immediate medical attention is required.


  5. FIRE-FIGHTING MEASURES


    1. Extinguishing Media


      Suitable extinguishing media


      Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.


    2. Special hazards arising from the substance or mixture


      In combustion, it may emit toxic fumes.


    3. Precautions for fire-fighters


      Wear suitable protective clothing to prevent contact with skin and eyes and self-contained breathing apparatus.


  6. ACCIDENTAL RELEASE MEASURES


    1. Personal precautions, protective equipment and emergency procedures


      Do not take action without suitable protective clothing - see section 8 of SDS. Evacuate personnel to safe areas. Ensure adequate ventilation. Avoid breathing vapours, mist, dust or gas.

    2. Environmental precautions


      Do not let product enter drains.


    3. Methods and materials for containment and cleaning up


      Cover spillage with suitable absorbent material. Hold all material for appropriate disposal as described under section 13 of SDS.

    4. Reference to other sections


      For required PPE see section 8. For disposal see section 13.


  7. HANDLING AND STORAGE


    1. Precautions for safe handling


      Avoid inhalation, contact with eyes, skin and clothing. Avoid the formation of dust and aerosols. Use in a well-ventilated area. Keep away from sources of ignition. Avoid prolonged or repeated exposure.

    2. Conditions for safe storage, including any incompatibilities


      Store in a cool, well-ventilated area. Keep away from direct sunlight. Keep the container tightly sealed until ready for use.


    3. Specific end uses


      Not applicable.


  8. EXPOSURE CONTROLS/PERSONAL PROTECTION


    1. Control parameters


      Components with workplace control parameters


      Contains no substances with occupational exposure limit values.


    2. Exposure controls Appropriate Engineering Controls

      Use in a fume hood where applicable. Ensure all engineering measures described under section 7 of SDS are in place. Ensure the laboratory is equipped with a safety shower and eyewash station.

      Personal Protective Equipment Eye / Face Protection


      Use appropriate safety glasses.


      Skin Protection


      Use appropriate chemical resistant gloves (minimum requirement use standard BS EN 374:2003). Gloves should be inspected before use. Wash and dry hands thoroughly after handling.

      Body Protection


      Wear appropriate protective clothing.


      Respiratory Protection


      If risk assessment indicates necessary, use a suitable respirator.

  9. PHYSICAL AND CHEMICAL PROPERTIES


    1. Information on basic physical and chemical properties


      Appearance

      Lyophilized white powder or clear liquid

      Vapour Pressure

      No data available.

      Odor

      Little to none

      Vapour Density

      No data available.

      Odor Threshold

      No data available.

      Relative Density

      No data available.

      pH

      No data available.

      Solubility(ies)

      No data available.

      Melting / Freezing Point

      No data available.

      Partition Coefficient

      No data available.

      Boiling Point / Range

      No data available.

      Autoignition Temperature

      No data available.


      Flash Point No data available. Decomposition Temperature No data available. Evaporation Rate No data available. Viscosity No data available. Flammability (Solid, Gas) No data available. Explosive Properties No data available. Upper / Lower Flammability or Explosive Limits No data available Oxidising Properties No data available.


    2. Other safety information


      No data available.


  10. STABILITY AND REACTIVITY


    1. Reactivity


      Stable under recommended transport or storage conditions.


    2. Chemical stability


      Stable under recommended storage conditions.


    3. Possibility of hazardous reactions


      Hazardous reactions will not occur under normal transport or storage conditions. Decomposition may occur on exposure to conditions or materials listed below.

    4. Conditions to avoid


      Heat, moisture.


    5. Incompatible materials


      Strong acids/alkalis, strong oxidising/reducing agents.


    6. Hazardous decomposition products


      Strong acids/alkalis, strong oxidising/reducing agents.



  11. TOXICOLOGICAL INFORMATION


    1. Information on toxicological effects Acute Toxicity

      Classified based on available data Skin Corrosion / Irritation Classified based on available data Serious Eye Damage / Irritation Classified based on available data Respiratory or Skin Sensitization Classified based on available data Germ Cell Mutagenicity Classified based on available data Carcinogenicity

      Classified based on available data


      Reproductive Toxicity


      Classified based on available data


      Specific Target Organ Toxicity - Single Exposure


      Classified based on available data


      Specific Target Organ Toxicity - Repeated Exposure


      Classified based on available data


      Aspiration Hazard


      Classified based on available data


      Symptoms / Routes of Exposure


      Inhalation: There may be irritation of the throat with a feeling of tightness in the chest. Ingestion: There may be irritation of the throat.

      Skin: There may be mild irritation at the site of contact.


      Eyes: There may be irritation and redness. Delayed / Immediate Effects: No known symptoms.

      Additional Information


      Classified based on available data


  12. ECOLOGICAL INFORMATION


    1. Toxicity


      No data available.



    2. Persistence and degradability


      No data available.


    3. Bioaccumulative potential


      No data available.


    4. Mobility in soil


      No data available.


    5. Results of PBT and vPvB assessment


      No data available.


    6. Other adverse effects


      No data available.


  13. DISPOSAL CONSIDERATIONS


    1. Waste treatment methods Product


      Transfer to a suitable container and arrange for collection by a specialised disposal company in accordance with national, regional, or local legislation.

      Contaminated Packaging


      Dispose of in a regulated landfill site or other method for hazardous or toxic wastes in accordance with national, regional, or local legislation.


  14. TRANSPORT INFORMATION


    Classified according to the criteria of the UN Model Regulations as reflected in the IMDG Code, ADR, RID, DOT and IATA.


    1. UN-Number


      Does not meet the criteria for classification as hazardous for transport.


    2. UN proper shipping name


      Does not meet the criteria for classification as hazardous for transport.


    3. Transport hazard class(es)


      Does not meet the criteria for classification as hazardous for transport.


    4. Packaging group


      Does not meet the criteria for classification as hazardous for transport.



    5. Environmental hazards

      Does not meet the criteria for classification as hazardous for transport.


    6. Special precautions for users


      Does not meet the criteria for classification as hazardous for transport.


      Additional Transport Information


      Does not meet the criteria for classification as hazardous for transport.



  15. REGULATORY INFORMATION


    This safety datasheet complies with the requirements of Regulation (EC) No. 453/2010.


    1. Safety, health and environmental regulations/legislation specific for the substance or mixture


      TSCA (Toxic Substances Control Act) : Not applicable. SARA 313 : Not applicable.

      SARA 311/312 : Not applicable.


      CERCLA Reportable Quantity : California Proposition 65 : Not applicable.


    2. Chemical safety assessment


      A Chemical Safety Assessment has not been made for this product.


  16. OTHER INFORMATION


Further Information


Copyright © 2022 ichorbio Ltd


This company shall not be held liable for any damage resulting from handling or from contact with the above product. This material must only be handled by suitably qualified experienced scientists in appropriately equipped and authorised facilities. The above information is believed to be correct but does not purport to be all inclusive and should be used as a guide only for experienced personnel. Always consult your safety advisor and follow appropriate local and national safety legislation. The absence of warning must not, under any circumstance, be taken to mean that no hazard exists.

End of safety data sheet