Odronextamab Biosimilar – Research Grade
ichorbio’s Odronextamab Biosimilar – Research Grade is for Research Use Only (RUO) and not for therapeutic use.
CD3/CD20
ichorbio’s biosimilars are available in the following sizes:
1mg, 5mg, 10mg, 20mg, 50mg, 100mg
Human IgG4
REGN 1979
CHO cells
Human
Detects human CD3/CD20. This non-therapeutic antibody uses the same sequence as the therapeutic antibody odronextamab.
This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
ichorbio’s Odronextamab biosimilar is a hinge-stabilized, fully human IgG4-based CD3 x CD20 bispecific antibody (bsAb). The drug has demonstrated encouraging safety, tolerability and preliminary efficacy in a first-in-human study of patients with relapsed/refractory B-cell non-Hodgkin lymphoma.
5mg/ml
Sterile, preservative-free, solution in PBS. BSA and Azide free.
>95% by SDS-PAGE
≤ 1.0 EU/mg as determined by the LAL method
This antibody is stable for at least 4 weeks when stored at 2-8°C. For long term storage, aliquot in working volumes without diluting and store at – 20°C or -80°C. Avoid repeated freeze thaw cycles.
Functional Assays
This biosimilar is for research use only (RUO): it is not for diagnostic or therapeutic procedures and cannot be purchased by patients.
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