Obinutuzumab Biosimilar – Research Grade [ICH4026]

ichorbio’s Obinutuzumab Biosimilar – Research Grade is manufactured in a cGMP compliant facility. ichorbio: the best antibodies for in vivo research.

ichorbio’s research grade obinutuzumab biosimilar is available in the following sizes:
5mg, 10mg, 20mg, 50mg
ichorbio regularly manufactures bulk multi-gram amounts of our obinutuzumab biosimilar – please contact us for pricing.

CD20

n/a

IgG1

B-lymphocyte surface antigen B1, Bp35, Leukocyte surface antigen Leu-16, Membrane-spanning 4-domains subfamily A member 1, MS4A1, afutuzumab

Humanized

Human

Detects human CD20. This non-therapeutic antibody uses the same variable region sequence as the therapeutic antibody Obinutuzumab/afutuzumab. This product is for research use only.

This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.

Obinutuzumab biosimilar is a humanized anti-CD20 monoclonal antibody of the IgG1 subclass. It recognizes a specific epitope of the CD20 molecule found on B cells. The molecular mass of the antibody is approximately 150 kDa. it is produced by mammalian cell (CHO) suspension culture. It was engineered for reduced fucose content as compared to a typical IgG1 produced in CHO cells.

1.0 – 5.0 mg/ml

Sterile, clear, colorless to brownish, preservative-free solution, containing Histidine/L-histidine hydrochloride, trehalose and 0.02% poloxamer 188, pH 6.0. BSA and Azide free.

>95% by SDS-PAGE and HPLC

≤ 0.75 EU/mg as determined by the LAL method

Obinutuzumab Biosimilar – Research Grade is stable for at least four (4) weeks when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at –80°C. Avoid Repeated Freeze Thaw Cycles.

Functional Assays

Each investigator should determine their own optimal working dilution for specific applications.