Monalizumab Biosimilar - Research Grade [ICH5017]

Monalizumab Biosimilar - Research Grade

Product Details:

ichorbio's monalizumab biosimilar is for Research Use Only (RUO)

Size:

ichorbio's RUO monalizumab biosimilar is available in the following sizes: 1mg, 5mg, 10mg, 20mg, 50mg, 100mg ichorbio regularly manufactures bulk multi-gram amounts of this biosimilar - please contact us for pricing.

Target:

NKG2A

Isotype:

IgG4

Other Names:

KLRC1, CD159a, CD94

Host:

CHO cells

Species Reactivity:

Human

Specificity:

Detects human NKG2A.

Purification Method:

This recombinant protein was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.

Background:

RUO monalizumab is a blocking antibody that prevents the inhibition of CD8+ T cells and NK cell by tumor cells expressing HLA-E. By acting simultaneously on innate and adaptive immunity, monalizumab may re-establish a broad anti-tumor response.

Concentration:

1.0 - 5.0 mg/ml

Formulation:

Sterile, preservative-free, solution in PBS. BSA and Azide free.

Purity:

>95% by SDS-PAGE and HPLC

Endotoxin:

≤ 1.0 EU/mg as determined by the LAL method

Storage:

Monalizumab Biosimilar - Research Grade is stable for at least four (4) weeks when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at –80°C. Avoid Repeated Freeze Thaw Cycles.

Applications:

Functional Assays

Application Notes:

Each investigator should determine their own optimal working dilution for specific applications.

Isotype Control:

Bulk Human IgG4 Isotype Control (IB4) [ICH2257]

Use: ichorbio's monalizumab biosimilar is for research use only (RUO).