Glofitamab Biosimilar - Research Grade

Glofitamab Biosimilar - Research Grade

Product Details:

ichorbio's glofitamab biosimilar is for Research Use Only (RUO)

Size:

ichorbio's RUO glofitamab biosimilar is available in the following sizes: 1mg, 5mg, 10mg, 20mg ichorbio regularly manufactures bulk multi-gram amounts of this biosimilar - please contact us for pricing.

Target:

CD3/CD20

Isotype:

IgG1

Other Names:

RO7082859, RG6026

Host:

CHO

Species Reactivity:

Human

Specificity:

Detects human CD3/CD20.

Purification Method:

This recombinant protein was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.

Background:

RUO glofitamab is a T-cell-engaging bispecific antibody possessing a novel 2:1 structure with bivalency for CD20 on B cells and monovalency for CD3 on T cells.

Concentration:

1.0 - 5.0 mg/ml

Formulation:

Sterile, preservative-free, solution in PBS. BSA and Azide free.

Purity:

>95% by SDS-PAGE and HPLC

Endotoxin:

≤ 1.0 EU/mg as determined by the LAL method

Storage:

Glofitamab biosimilar - Research Grade is stable for at least four (4) weeks when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at –80°C. Avoid Repeated Freeze Thaw Cycles.

Applications:

Functional Assays

Application Notes:

Each investigator should determine their own optimal working dilution for specific applications.

Isotype Control:

Bulk Human IgG1 Isotype Control (IB1) [ICH2254]

Use: ichorbio's glofitamab biosimilar is for research use only (RUO).