Evolocumab Biosimilar – Research Grade [ICH4023]

ichorbio’s Evolocumab Biosimilar – Research Grade is manufactured in a cGMP compliant facility. ichorbio: the best antibodies for in vivo research.

ichorbio’s research grade evolocumab biosimilar is available in the following sizes:
5mg, 10mg, 20mg, 50mg, 100mg
ichorbio regularly manufactures bulk multi-gram amounts of our evolocumab biosimilar – please contact us for pricing.

PCSK9

n/a

IgG2

Proprotein convertase subtilisin/kexin type 9, NARC-1, PC9

Humanized

Human

Detects human PCSK9. This non-therapeutic antibody uses the same variable region sequence as the therapeutic antibody Evolocumab. This product is for research use only.

This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.

Evolocumab biosimilar is a human monoclonal immunoglobulin G2 (IgG2) directed against human proprotein convertase subtilisin kexin 9 (PCSK9). Evolocumab biosimilarhas an approximate molecular weight (MW) of 144 kDa and is produced in genetically engineered mammalian (Chinese hamster ovary) cells.

1.0 – 5.0 mg/ml

Sterile, preservative-free, clear or milky white, colorless to pale yellow solution, containing acetic acid, Polysorbate 80 and proline. pH of the buffer is 5.0. BSA and Azide free.

>95% by SDS-PAGE and HPLC

≤ 0.75 EU/mg as determined by the LAL method

Evolocumab Biosimilar – Research Grade is stable for at least four (4) weeks when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at –80°C. Avoid Repeated Freeze Thaw Cycles.

Functional Assays

Each investigator should determine their own optimal working dilution for specific applications.