Cetuximab Biosimilar – Research Grade [ICH4004]

ichorbio’s Cetuximab Biosimilar – Research Grade is manufactured in a cGMP compliant facility. ichorbio: the best antibodies for in vivo research.

ichorbio’s research grade cetuximab biosimilar is available in the following sizes:
5mg, 10mg, 20mg, 50mg
ichorbio regularly manufactures bulk multi-gram amounts of our cetuximab biosimilar – please contact us for pricing.

EGFR

n/a

IgG1

Epidermal growth factor receptor, Proto-oncogene c-ErbB-1, Receptor tyrosine-protein kinase erbB-1, ERBB, ERBB1, HER1

Humanized

Human

Detects human EGFR. This non-therapeutic antibody uses the same variable region sequence as the therapeutic antibody Cetuximab. This product is for research use only.

This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.

Cetuximab biosimilar is a recombinant, human/mouse chimeric monoclonal antibody that binds specifically to the extracellular domain of the human epidermal growth factor receptor (EGFR). Cetuximab biosimilar is composed of the Fv regions of a murine anti-EGFR antibody with human IgG1 heavy and kappa light chain constant regions and has an approximate molecular weight of 152 kDa. Cetuximab biosimilar is produced in mammalian (Chinese Hamster Ovary) cell culture.

1.0 – 5.0 mg/ml

Sterile, transparent, colorless, preservative-free liquid with a pH value of 7.0 to 7.4, which contains Sodium chloride, disodium hydrogen phosphate heptahydrate, sodium dihydrogen phosphate monohydrate. BSA and Azide free.

>95% by SDS-PAGE and HPLC

≤ 0.75 EU/mg as determined by the LAL method

Cetuximab Biosimilar – Research Grade is stable for at least four (4) weeks when stored sterile at 2-8°C.

Functional Assays

Each investigator should determine their own optimal working dilution for specific applications.