Bulk anti-human CD64 antibody (10.1) [ICH1167]

ichorbio’s bulk anti-human CD64 antibody (10.1) is manufactured in a cGMP compliant, ISO Quality Standard 9001:2015 facility. ichorbio’s low endotoxin antibodies have half the endotoxin of comparable antibodies from our competitors at less than 1.0 EU/mg. If ichorbio’s low endotoxin antibodies are not low enough we also offer ultra low endotoxin antibodies which have even less endotoxin (<0.75EU/mg) at an even higher purity (98% versus 95%). ichorbio: the best antibodies for in vivo research.

CD64

Fc-gamma receptor 1, FcγRI, Fc Gamma Receptor Ia, Fc-Gamma RIA, CD64

10.1

ichorbio’s 10.1 in vivo antibody is available in the following bulk sizes:
1mg, 5mg, 25mg, 50mg and 100mg
ichorbio regularly manufactures multi-gram amounts of our anti-CD64 10.1 clone – please contact us for pricing.

Mouse IgG1 κ

P12314

Mouse

Human

Clone 10.1 recognizes an epitope on human FcγRI

This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.

FcγRI (CD64) is an IgG receptor expressed by monocytes and myeloid cell lines.

Fc gamma receptors (FcγRs) are membrane-bound proteins which control and mediate communication of IgG antibodies within the immune system. These receptors play a crucial role in the link between the innate and adaptive immune system. FcγRI, CD64, is expressed on dendritic cells, macrophages/monocytes, and granulocytes. Of the FcγRs, FcγRI is capable of interacting with monomeric IgG with relatively high affinity.

Rheumatoid synovial fluid cells and fibronectin purified human monocytes

>2.0 mg/ml

This monoclonal antibody is aseptically packaged and formulated in 0.01 M phosphate buffered saline (PBS) pH 7.2 – 7.4, 150 mM NaCl with no carrier protein, potassium or preservatives added. BSA and azide free

>95% by SDS-PAGE and HPLC

>98% by SDS-PAGE and HPLC

≤ 1.0 EU/mg as determined by the LAL method

≤ 0.75 EU/mg as determined by the LAL method

Aggregation level ≤ 5%

Aggregation level ≤ 1%

TThis antibody is stable for at least 4 weeks when stored at 2-8°C. For long term storage, aliquot in working volumes without diluting and store at – 20°C or -80°C. Avoid repeated freeze thaw cycles.

Blocking, Functional Assays, Flow Cytometry, Immunofluorescence, Immunohistochemistry – Frozen, Immunoprecipitation

Each investigator should determine their own optimal working dilution for specific applications.

Products are for research use only. Not for use in diagnostic or therapeutic procedures.