Anti-Mouse CD370 In Vivo Antibody – Low Endotoxin (1F6) [ICH1168]

ichorbio’s anti- CD370 In Vivo Antibody – Low Endotoxin (1F6) is manufactured in a cGMP compliant, ISO Quality Standard 9001:2015 facility. ichorbio’s low endotoxin antibodies have half the endotoxin of comparable antibodies from our competitors at less than 1.0 EU/mg. If ichorbio’s low endotoxin antibodies are not low enough we also offer ultra low endotoxin antibodies which have even less endotoxin (<0.75EU/mg) at an even higher purity (98% versus 95%). ichorbio: the best antibodies for in vivo research.

CD370

CD370, DNGR-1, C-Type Lectin Domain Family 9 Member A

1F6

ichorbio’s 1F6 in vivo antibody is available in the following bulk sizes:
1mg, 5mg, 25mg, 50mg and 100mg
ichorbio regularly manufactures multi-gram amounts of our anti-CD370 1F6 clone – please contact us for pricing.

Rat IgG1

Q8BRU4

Rat

Mouse

Clone 1F6 recognizes an epitope on mouse DNGR1

This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.

CD370 (CLEC9A) in mice is expressed on CD8+ DCs and at low levels by plasmacytoid DCs.

CLEC9A, also known as DNGR1 is defined as a type II membrane protein with a single extracellular C-type lectin domain¹. CLEC9A is involved with adaptive immune response during infection. Additionally, CLEC9A, is being investigated for potential to enhance immune responses produced by vaccines.

RBL-2H3 cells expressing mouse DNGR-1 fused to an HA epitope.

>2.0 mg/ml

This monoclonal antibody is aseptically packaged and formulated in 0.01 M phosphate buffered saline (PBS) pH 7.2 – 7.4, 150 mM NaCl with no carrier protein, potassium or preservatives added. BSA and azide free

>95% by SDS-PAGE and HPLC

>98% by SDS-PAGE and HPLC

≤ 1.0 EU/mg as determined by the LAL method

≤ 0.75 EU/mg as determined by the LAL method

Aggregation level ≤ 5%

Aggregation level ≤ 1%

This antibody is stable for at least 4 weeks when stored at 2-8°C. For long term storage, aliquot in working volumes without diluting and store at – 20°C or -80°C. Avoid repeated freeze thaw cycles.

Flow Cytometry, Immunofluorescence, Western Blotting

Each investigator should determine their own optimal working dilution for specific applications.

Products are for research use only. Not for use in diagnostic or therapeutic procedures.