Bulk anti-Human iNKT cell antibody (6B11) [ICH1032]

ichorbio’s anti-human iNKT cell antibody (6B11) is manufactured in a cGMP compliant, ISO Quality Standard 9001:2015 facility. ichorbio’s low endotoxin antibodies have half the endotoxin of comparable antibodies from our competitors at less than 1.0 EU/mg. If ichorbio’s low endotoxin antibodies are not low enough we also offer ultra low endotoxin antibodies which have even less endotoxin (<0.75EU/mg) at an even higher purity (98% versus 95%). ichorbio: the best antibodies for in vivo research.

iNKT cell

6B11

Mouse IgG1

TCR Valpha24-Jalpha18, TCR Valpha24-JalphaQ, invariant NKT cell, iNKT

Mouse

Human

Bulk anti-human iNKT cell antibody (6B11) recognizes an epitope on TCR V alpha 24-J alpha 18

This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.

Invariant NKT cells

Encoded by the TCR V alpha 24-J alpha 18 germline configuration, V alpha 24-J alpha Q is expressed on a subset of NKT cells, namely invariant NKT (iNKT). V alpha 24-J alpha Q TCR interacts with the glycolipid loaded MHC class 1b molecule CD1d, inducing activation and subsequent cytokine production.

Unknown

1.0 – 5.0 mg/ml

0.01 M phosphate buffered saline (PBS) pH 7.2, 150 mM NaCl with no carrier protein, potassium or preservatives added. BSA and Azide free.

>95% by SDS-PAGE and HPLC

>98% by SDS-PAGE and HPLC

≤ 1.0 EU/mg as determined by the LAL method

≤ 0.75 EU/mg as determined by the LAL method

Aggregation level ≤ 5%

Aggregation level ≤ 1%

This antibody is stable for at least 4 weeks when stored at 2-8°C. For long term storage, aliquot in working volumes without diluting and store at – 20°C or -80°C. Avoid repeated freeze thaw cycles.

Western Blot, Flow Cytometry

Each investigator should determine their own optimal working dilution for specific applications.

Products are for research use only. Not for use in diagnostic or therapeutic procedures.

Mouse IgG1 Isotype Control for In Vivo – Low Endotoxin [HKSP] (ICH2247)