Bulk anti-IFN gamma In Vivo Antibody – Low Endotoxin (XMG1.2)
ICH1141 is up to 30% cheaper for academia & non-profits and up to 55% cheaper for industry than the equivalent low endotoxin product (BE0055) from Bio X Cell. ICH1141UL is up to 31% cheaper for academia and up to 56% cheaper for industry compared to the ultra-low endotoxin version from Bio X Cell (BP0055).
ichorbio’s anti-IFN gamma In Vivo Antibody – Low Endotoxin (XMG1.2) is manufactured in a cGMP compliant, ISO Quality Standard 9001:2015 facility. ichorbio’s low endotoxin antibodies have half the endotoxin of comparable antibodies from our competitors at less than 1.0 EU/mg. If ichorbio’s low endotoxin antibodies are not low enough we also offer ultra low endotoxin antibodies which have even less endotoxin (<0.75EU/mg) at an even higher purity (98% versus 95%). ichorbio: the best antibodies for in vivo research.
ichorbio’s XMG1.2 in vivo antibody is available in the following bulk sizes:
1mg, 5mg, 25mg, 50mg and 100mg
ichorbio regularly manufactures multi-gram amounts of our anti-IFN gamma XMG1.2 clone – please contact us for pricing.
Interferon gamma, Ifng
Anti-IFN gamma In Vivo Antibody – Low Endotoxin (XMG1.2) recognizes an epitope on Mouse IFN-gamma
This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
Interferon-gamma (IFN-γ) or type II interferon is a dimerized soluble cytokine that is the only member of the type II class of interferons. It is a cytokine critical for innate and adaptive immunity against viral and intracellular bacterial infections and for tumor control. IFNG is produced predominantly by natural killer (NK) and natural killer T (NKT) cells as part of the innate immune response, and by CD4 and CD8 cytotoxic T lymphocyte (CTL) effector T cells once antigen-specific immunity develops. IFNG has antiviral, immunoregulatory, and anti-tumour properties.
Purified Recombinant Mouse IFN-gamma (>98%)
0.01 M phosphate buffered saline (PBS) pH 7.2, 150 mM NaCl with no carrier protein, potassium or preservatives added. BSA and Azide free.
>95% by SDS-PAGE and analyzed by silver stain.
>98% by SDS-PAGE and HPLC
<1.0 EU/mg as determined by the LAL method
≤ 0.75 EU/mg as determined by the LAL method
Aggregation level ≤ 5%
Aggregation level ≤ 1%
anti-IFN gamma In Vivo Antibody – Low Endotoxin (XMG1.2) is stable for at least one week when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at –80°C. Avoid Repeated Freeze Thaw Cycles.
ELISA Capture, ELISPOT, IHC (Frozen), Neutralization, Western Blot, CyTOF
Each investigator should determine their own optimal working dilution for specific applications.
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
Immunofluorescence analysis of paraffin-embedded breast cancer tissue section labeling IFN-g (1:100) overnight at 4˚, followed by goat anti-mouse IgG H&L (Alexa Fluor ® 647-red) secondary antibody (1:500 dilution).. MDA-MB-231 cells were injected via mouse nipple and grown for 5 weeks. Image was acquired on a Nikon A1R microscope system at 4x magnification (first image) or 60x magnification (second image).