Bulk Alemtuzumab Biosimilar – Research Grade
ichorbio’s Alemtuzumab Biosimilar – Research Grade is manufactured in a cGMP compliant facility. Our alemtuzumab biosimilar is for research use only (RUO).
ichorbio’s research grade alemtuzumab biosimilar is available in the following sizes:
5mg, 10mg, 20mg, 50mg, 100mg
ichorbio regularly manufactures bulk multi-gram amounts of our alemtuzumab biosimilar – please contact us for pricing.
CD52
n/a
IgG1 kappa
Campath-1 antigen, Cambridge pathology 1 antigen, HE5
Humanized
Human
Detects human CD52. This non-therapeutic antibody uses the same variable region sequence as the therapeutic antibody Alemtuzumab.
This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
Alemtuzumab biosimilar is a recombinant DNA-derived humanized monoclonal antibody (Campath-1H) directed against the 21-28 kD cell surface glycoprotein, CD52, is an IgG1 kappa antibody with human variable framework and constant regions, and complementarity-determining regions from a murine (rat) monoclonal antibody. The alemtuzumab biosimilar has an approximate molecular weight of 150 kD and is produced in mammalian cell (Chinese hamster ovary) suspension culture in a medium.
1.0 – 5.0 mg/ml
Sterile, clear, colorless, preservative-free solution with a pH value of 6.8-7.4 and contains sodium chloride, disodium hydrogen phosphate, potassium chloride, potassium dihydrogen phosphate, polysorbate 80 and EDTA two sodium. BSA and Azide free.
>95% by SDS-PAGE and HPLC
≤ 0.75 EU/mg as determined by the LAL method
Alemtuzumab Biosimilar – Research Grade is stable for at least four (4) weeks when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at –80°C. Avoid Repeated Freeze Thaw Cycles.
Functional Assays
Each investigator should determine their own optimal working dilution for specific applications.
ichorbio’s alemtuzumab biosimilar is for research use only (RUO): it is not for diagnostic or therapeutic procedures and cannot be purchased by patients.