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2020 FDA Approvals for Alemtuzumab

Alemtuzumab Biosimilar – Research Grade [ICH4002]

Rated 5.00 out of 5 based on 1 customer rating

$718.00 – $4,161.00

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2020 FDA Approvals for Alemtuzumab
Alemtuzumab Biosimilar – Research Grade [ICH4002]
SKU: ICH4002 Categories: anti-human, Biosimilar Antibodies, Low Endotoxin
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Bulk Alemtuzumab Biosimilar – Research Grade

Product Benefits:

ichorbio’s Alemtuzumab Biosimilar – Research Grade is manufactured in a cGMP compliant facility. Our alemtuzumab biosimilar is for research use only (RUO).

Size:

ichorbio’s research grade alemtuzumab biosimilar is available in the following sizes:
5mg, 10mg, 20mg, 50mg
ichorbio regularly manufactures bulk multi-gram amounts of our alemtuzumab biosimilar – please contact us for pricing.

Target:

CD52

Clone:

n/a

Isotype:

IgG1 kappa

Other Names:

Campath-1 antigen, Cambridge pathology 1 antigen, HE5

Host:

Humanized

Species Reactivity:

Human

Specificity:

Detects human CD52. This non-therapeutic antibody uses the same variable region sequence as the therapeutic antibody Alemtuzumab.

Purification Method:

This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.

Background:

Alemtuzumab biosimilar is a recombinant DNA-derived humanized monoclonal antibody (Campath-1H) directed against the 21-28 kD cell surface glycoprotein, CD52, is an IgG1 kappa antibody with human variable framework and constant regions, and complementarity-determining regions from a murine (rat) monoclonal antibody. The alemtuzumab biosimilar has an approximate molecular weight of 150 kD and is produced in mammalian cell (Chinese hamster ovary) suspension culture in a medium.

Concentration:

1.0 – 5.0 mg/ml

Formulation:

Sterile, clear, colorless, preservative-free solution with a pH value of 6.8-7.4 and contains sodium chloride, disodium hydrogen phosphate, potassium chloride, potassium dihydrogen phosphate, polysorbate 80 and EDTA two sodium. BSA and Azide free.

Purity:

>95% by SDS-PAGE and HPLC

Endotoxin:

≤ 0.75 EU/mg as determined by the LAL method

Storage:

Alemtuzumab Biosimilar – Research Grade is stable for at least four (4) weeks when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at –80°C. Avoid Repeated Freeze Thaw Cycles.

Applications:

Functional Assays

Application Notes:

Each investigator should determine their own optimal working dilution for specific applications.

Use:

ichorbio’s alemtuzumab biosimilar is for research use only (RUO): it is not for diagnostic or therapeutic procedures and cannot be purchased by patients.

Size:

0.1mg, 1mg, 2mg, 5mg, 10mg, 20mg, 50mg

Endotoxin Level:

Low

1 review for Alemtuzumab Biosimilar – Research Grade [ICH4002]

  1. Rated 5 out of 5

    Anonymous – March 17, 2021

    This is a great product. Highly cytotoxic in both ADCC and CDC. We have used in in a great variety of immune assays and with several CD52+ target cells.

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