Aducanumab Biosimilar - Research Grade

Aducanumab Biosimilar - Research Grade

Product Details:

ichorbio's aducanumab biosimilar is for Research Use Only (RUO)

Size:

ichorbio's RUO aducanumab biosimilar is available in the following sizes: 1mg, 5mg, 10mg, 20mg, 50mg, 100mg ichorbio regularly manufactures bulk multi-gram amounts of this biosimilar - please contact us for pricing.

Target:

Amyloid Beta

Isotype:

IgG1 kappa

Other Names:

Aducanumab-avwa, BIIB037, BIIB-037

Host:

CHO cells

Species Reactivity:

Human

Specificity:

Detects human amyloid beta.

Purification Method:

This recombinant protein was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.

Background:

RUO Aducanumab is a human monoclonal antibody that selectively targets aggregated amyloid beta. In a transgenic mouse model of Alzheimer's disease, aducanumab is shown to enter the brain, bind parenchymal amyloid beta, and reduce soluble and insoluble amyloid beta in a dose-dependent manner.

Concentration:

1.0 - 5.0 mg/ml

Formulation:

Sterile, preservative-free, solution in PBS. BSA and Azide free.

Purity:

>95% by SDS-PAGE and HPLC

Endotoxin:

≤ 1.0 EU/mg as determined by the LAL method

Storage:

Aducanumab Biosimilar - Research Grade is stable for at least four (4) weeks when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at –80°C. Avoid Repeated Freeze Thaw Cycles.

Applications:

Functional Assays

Application Notes:

Each investigator should determine their own optimal working dilution for specific applications.

Use: ichorbio's aducanumab biosimilar is for research use only (RUO).