Aducanumab Biosimilar – Research Grade [ICH5008]

ichorbio’s aducanumab biosimilar is for Research Use Only (RUO) and not for therapeutic use.

ichorbio’s RUO aducanumab biosimilar is available in the following sizes:
1mg, 5mg, 10mg, 20mg, 50mg, 100mg
ichorbio regularly manufactures bulk multi-gram amounts of this biosimilar – please contact us for pricing.

Amyloid Beta

IgG1 kappa

Aducanumab-avwa, BIIB037, BIIB-037

CHO cells

Human

Detects human amyloid beta. This non-therapeutic antibody uses the same sequence as the therapeutic antibody aducanumab.

This recombinant protein was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.

RUO Aducanumab is a human monoclonal antibody that selectively targets aggregated amyloid beta. In a transgenic mouse model of Alzheimer’s disease, aducanumab is shown to enter the brain, bind parenchymal amyloid beta, and reduce soluble and insoluble amyloid beta in a dose-dependent manner.

1.0 – 5.0 mg/ml

Sterile, preservative-free, solution in PBS. BSA and Azide free.

>95% by SDS-PAGE and HPLC

≤ 1.0 EU/mg as determined by the LAL method

Aducanumab Biosimilar – Research Grade is stable for at least four (4) weeks when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at –80°C. Avoid Repeated Freeze Thaw Cycles.

Functional Assays

Each investigator should determine their own optimal working dilution for specific applications.