Anti-Mouse LAG-3 In Vivo Antibody – Low Endotoxin (C9B7W) [ICH1078]

ichorbio’s anti-LAG-3 In Vivo Antibody – Low Endotoxin (C9B7W) is manufactured in a cGMP compliant, ISO Quality Standard 9001:2015 facility. ichorbio’s low endotoxin antibodies have half the endotoxin of comparable antibodies from our competitors at less than 1.0 EU/mg. If ichorbio’s low endotoxin antibodies are not low enough we also offer ultra low endotoxin antibodies which have even less endotoxin (<0.75EU/mg) at an even higher purity (98% versus 95%). ichorbio: the best antibodies for in vivo research.

LAG3

C9B7W

ichorbio’s C9B7W in vivo antibody is available in the following bulk sizes:
1mg, 5mg, 25mg, 50mg and 100mg
ichorbio regularly manufactures multi-gram amounts of our anti-LAG-3 C9B7W clone – please contact us for pricing.

Rat IgG1

Lymphocyte activation gene 3 protein, Aida, CD223

Q61790

Rat

Mouse, Rat

Anti-LAG-3 In Vivo Antibody – Low Endotoxin (C9B7W) recognizes an epitope on Mouse LAG-3

This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.

T-cells and NK cells

LAG-3, also known as CD223, is 70 kD type I transmembrane glycoprotein within the Ig superfamily. CD223, like CD4, binds MHC class II molecules, but with higher affinity than CD4. Clone C9B7W antibody has been reported to block the function of murine LAG-3 in vivo and in vitro.

Murine CD223-Ig fusion protein

1.0 – 5.0 mg/ml

0.01 M phosphate buffered saline (PBS) pH 7.2, 150 mM NaCl with no carrier protein, potassium or preservatives added. BSA and Azide free.

>95% by SDS-PAGE and HPLC

>98% by SDS-PAGE and HPLC

≤ 1.0 EU/mg as determined by the LAL method

≤ 0.75 EU/mg as determined by the LAL method

Aggregation level ≤ 5%

Aggregation level ≤ 1%

This antibody is stable for at least 4 weeks when stored at 2-8°C. For long term storage, aliquot in working volumes without diluting and store at – 20°C or -80°C. Avoid repeated freeze thaw cycles.

Western Blot, Blocking, Flow Cytometry, Immunoprecipitation, ELISA

Blocking: Clone C9B7W antibody blocks the function of murine LAG-3 in vivo.
Each investigator should determine their own optimal working dilution for specific applications.

Products are for research use only. Not for use in diagnostic or therapeutic procedures.

Rat IgG1 Isotype Control for In Vivo – Low Endotoxin [GL113] (ICH2246)